Varaico: Literature-Extracted Genetic Variants

HLA-DPB1

170 papers

RefSeq Summary

HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a centra...

Pfam Domains

MHC_II_betaaa 42–114UCSCClass II histocompatibility antigen, beta domain

C1-setaa 126–207UCSCImmunoglobulin C1-set domain

Gene Aliases

HGNC Name

major histocompatibility complex, class II, DP beta 1

HGNC Previous Symbol

HLA-DP1B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_002121.6

p.A46E

c.137C>A

Surrounding Variants

1 paper

NM_002121.6

p.A46P

c.136G>C

1 paper

NM_002121.6

p.F47_N48insCT

c.139_143ins6

1 paper

NM_002121.6

p.N48Y

c.142A>T

1 paper

NM_002121.6

p.G49G

c.147G>C

1 paper

NM_002121.6

p.Q42E

c.124C>G

2 papers

NM_002121.6

p.G40V

c.119G>T

5 papers

NM_002121.6

p.G40*

c.118G>T

1 paper

NM_002121.6

p.F53F

c.159C>T

1 paper

NM_002121.6

p.F38L

c.114C>A

1 paper

NM_002121.6

p.F38L

c.114C>G

3 papers

NM_002121.6

p.F38Y

c.113T>A

3 papers

NM_002121.6

p.F38L

c.112T>C