Varaico: Literature-Extracted Genetic Variants

HLA-DPB1

170 papers

RefSeq Summary

HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a centra...

Pfam Domains

MHC_II_betaaa 42–114UCSCClass II histocompatibility antigen, beta domain

C1-setaa 126–207UCSCImmunoglobulin C1-set domain

Gene Aliases

HGNC Name

major histocompatibility complex, class II, DP beta 1

HGNC Previous Symbol

HLA-DP1B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_002121.6

p.R61P

c.182G>C

Surrounding Variants

5 papers

NM_002121.6

p.E62Q

c.184G>C

1 paper

NM_002121.6

p.N60D

c.178A>G

1 paper

NM_002121.6

p.Y59H

c.175T>C

4 papers

NM_002121.6

p.F64L

c.190T>C

5 papers

NM_002121.6

p.F64Y

c.191T>A

4 papers

NM_002121.6

p.F64L

c.192C>A

4 papers

NM_002121.6

p.F64L

c.192C>G

1 paper

NM_002121.6

p.A65G

c.194C>G

5 papers

NM_002121.6

p.A65V

c.194C>T

2 papers

NM_002121.6

p.Y57D

c.169T>G

2 papers

NM_002121.6

p.R66C

c.196C>T

1 paper

NM_002121.6

p.F67Y

c.200T>A