Varaico: Literature-Extracted Genetic Variants

HLA-DPB1

170 papers

RefSeq Summary

HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a centra...

Pfam Domains

MHC_II_betaaa 42–114UCSCClass II histocompatibility antigen, beta domain

C1-setaa 126–207UCSCImmunoglobulin C1-set domain

Gene Aliases

HGNC Name

major histocompatibility complex, class II, DP beta 1

HGNC Previous Symbol

HLA-DP1B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002121.6

p.F74Y

c.221T>A

Surrounding Variants

1 paper

NM_002121.6

p.R75G

c.223C>G

1 paper

NM_002121.6

p.R75Q

c.224G>A

1 paper

NM_002121.6

p.A76E

c.227C>A

1 paper

NM_002121.6

p.A76V

c.227C>T

1 paper

NM_002121.6

p.D68H

c.202G>C

1 paper

NM_002121.6

p.F67Y

c.200T>A

2 papers

NM_002121.6

p.R66C

c.196C>T

1 paper

NM_002121.6

p.R82R

c.246G>A

1 paper

NM_002121.6

p.P83delins

c.248delinsAAGTGTTTGC

1 paper

NM_002121.6

p.A65G

c.194C>G

5 papers

NM_002121.6

p.A65V

c.194C>T

4 papers

NM_002121.6

p.F64L

c.192C>A