Varaico: Literature-Extracted Genetic Variants

HLA-DPB1

170 papers

RefSeq Summary

HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a centra...

Pfam Domains

MHC_II_betaaa 42–114UCSCClass II histocompatibility antigen, beta domain

C1-setaa 126–207UCSCImmunoglobulin C1-set domain

Gene Aliases

HGNC Name

major histocompatibility complex, class II, DP beta 1

HGNC Previous Symbol

HLA-DP1B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_002121.6

p.I94L

c.280A>C

Surrounding Variants

1 paper

NM_002121.6

p.I94T

c.281T>C

1 paper

NM_002121.6

p.I94M

c.282C>G

2 papers

NM_002121.6

p.Q91Q

c.273G>A

1 paper

NM_002121.6

p.S90N

c.269G>A

11 papers

NM_002121.6

p.K98E

c.292A>G

2 papers

NM_002121.6

p.K98R

c.293A>G

1 paper

NM_002121.6

p.R99R

c.295C>A

2 papers

NM_002121.6

p.Y87H

c.259T>C

2 papers

NM_002121.6

p.E86D

c.258G>C

2 papers

NM_002121.6

p.E86D

c.258G>T

1 paper

NM_002121.6

p.P102Q

c.305C>A

1 paper

NM_002121.6

p.P102L

c.305C>T