Varaico: Literature-Extracted Genetic Variants

HLA-DPB1

170 papers

RefSeq Summary

HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a centra...

Pfam Domains

MHC_II_betaaa 42–114UCSCClass II histocompatibility antigen, beta domain

C1-setaa 126–207UCSCImmunoglobulin C1-set domain

Gene Aliases

HGNC Name

major histocompatibility complex, class II, DP beta 1

HGNC Previous Symbol

HLA-DP1B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002121.6

p.D103G

c.308A>G

Surrounding Variants

1 paper

NM_002121.6

p.P102Q

c.305C>A

1 paper

NM_002121.6

p.P102L

c.305C>T

1 paper

NM_002121.6

p.R104S

c.312G>C

1 paper

NM_002121.6

p.R104S

c.312G>T

8 papers

NM_002121.6

p.M105V

c.313A>G

8 papers

NM_002121.6

p.M105I

c.315G>A

6 papers

NM_002121.6

p.M105I

c.315G>C

6 papers

NM_002121.6

p.M105I

c.315G>T

1 paper

NM_002121.6

p.R107S

c.321A>T

1 paper

NM_002121.6

p.R99R

c.295C>A

2 papers

NM_002121.6

p.K98R

c.293A>G

11 papers

NM_002121.6

p.K98E

c.292A>G