Varaico: Literature-Extracted Genetic Variants

HLA-DPB1

170 papers

RefSeq Summary

HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a centra...

Pfam Domains

MHC_II_betaaa 42–114UCSCClass II histocompatibility antigen, beta domain

C1-setaa 126–207UCSCImmunoglobulin C1-set domain

Gene Aliases

HGNC Name

major histocompatibility complex, class II, DP beta 1

HGNC Previous Symbol

HLA-DP1B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_002121.6

p.R125K

c.374G>A

Surrounding Variants

1 paper

NM_002121.6

p.N127T

c.380A>C

2 papers

NM_002121.6

p.N127N

c.381T>C

1 paper

NM_002121.6

p.V122Splc

c.365-4C>G

1 paper

NM_002121.6

p.P130S

c.388C>T

2 papers

NM_002121.6

p.P130P

c.390C>A

1 paper

NM_002121.6

p.V122Splc

c.365-8G>A

1 paper

NM_002121.6

p.V122Splc

c.365-10A>C

1 paper

NM_002121.6

p.K133N

c.399G>C

1 paper

NM_002121.6

p.K133N

c.399G>T

1 paper

NM_002121.6

p.G134R

c.400G>A

1 paper

NM_002121.6

p.G134R

c.400G>C

1 paper

NM_002121.6

p.T147T

c.441G>A