Varaico: Literature-Extracted Genetic Variants

HLA-DPB1

170 papers

RefSeq Summary

HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a centra...

Pfam Domains

MHC_II_betaaa 42–114UCSCClass II histocompatibility antigen, beta domain

C1-setaa 126–207UCSCImmunoglobulin C1-set domain

Gene Aliases

HGNC Name

major histocompatibility complex, class II, DP beta 1

HGNC Previous Symbol

HLA-DP1B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002121.6

p.N173Y

c.517A>T

Surrounding Variants

1 paper

NM_002121.6

p.V170A

c.509T>C

1 paper

NM_002121.6

p.R176C

c.526C>T

1 paper

NM_002121.6

p.A167G

c.500C>G

4 papers

NM_002121.6

p.T166A

c.496A>G

1 paper

NM_002121.6

p.E164*

c.490G>T

1 paper

NM_002121.6

p.Q163Q

c.489G>A

1 paper

NM_002121.6

p.G162V

c.485G>T

2 papers

NM_002121.6

p.I184V

c.550A>G

1 paper

NM_002121.6

p.F159C

c.476T>G

1 paper

NM_002121.6

p.L188P

c.563T>C

1 paper

NM_002121.6

p.R157*

c.469C>T

1 paper

NM_002121.6

p.Q155R

c.464A>G