Varaico: Literature-Extracted Genetic Variants

HLA-DQB2

47 papers

RefSeq Summary

HLA-DQB2 belongs to the family of HLA class II beta chain paralogs. Class II molecules are heterodimers consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. They play a ...

Pfam Domains

MHC_II_betaaa 41–114UCSCClass II histocompatibility antigen, beta domain

C1-setaa 126–207UCSCImmunoglobulin C1-set domain

Gene Aliases

HGNC Name

major histocompatibility complex, class II, DQ beta 2

HGNC Previous Symbol

HLA-DXB

Papers

RefSeq ID

Protein change

DNA change

1–12 of 74 variants

8 papers

NM_001300790.2

p.R157Q

c.470G>A

5 papers

NM_001300790.2

p.S173P

c.517T>C

4 papers

NM_001300790.2

p.S228G

c.682A>G

4 papers

NM_001300790.2

p.R247H

c.740G>A

3 papers

NM_001300790.2

p.A112V

c.335C>T

3 papers

NM_001300790.2

p.Q121R

c.362A>G

3 papers

NM_001300790.2

p.A167T

c.499G>A

2 papers

NM_001300790.2

p.E63G

c.188A>G

2 papers

NM_001300790.2

p.E111Q

c.331G>C

2 papers

NM_001300790.2

p.A112S

c.334G>T

2 papers

NM_001300790.2

p.L174F

c.520C>T

2 papers

NM_001300790.2

p.G250S

c.748G>A