Varaico: Literature-Extracted Genetic Variants

HLA-DRB1

592 papers

RefSeq Summary

HLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central ...

Pfam Domains

MHC_II_betaaa 42–116UCSCClass II histocompatibility antigen, beta domain

C1-setaa 128–209UCSCImmunoglobulin C1-set domain

Gene Aliases

HGNC Name

major histocompatibility complex, class II, DR beta 1

HGNC Previous Symbol

HLA-DR1B

Papers

RefSeq ID

Protein change

DNA change

1–12 of 604 variants

15 papers

NM_002124.4

p.A169T

c.505G>A

13 papers

NM_002124.4

p.V67A

c.200T>C

13 papers

NM_002124.4

p.T106N

c.317C>A

12 papers

NM_002124.4

p.K5R

c.14A>G

12 papers

NM_002124.4

p.T80R

c.239C>G

12 papers

NM_002124.4

p.S133A

c.397T>G

11 papers

NM_002124.4

p.Q39*

c.115C>T

11 papers

NM_002124.4

p.Q178H

c.534G>C

10 papers

NM_002124.4

p.M20T

c.59T>C

10 papers

NM_002124.4

p.S66Y

c.197C>A

10 papers

NM_002124.4

p.V115G

c.344T>G

10 papers

NM_002124.4

p.T135N

c.404C>A