Varaico: Literature-Extracted Genetic Variants

HLA-DRB1

592 papers

RefSeq Summary

HLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central ...

Pfam Domains

MHC_II_betaaa 42–116UCSCClass II histocompatibility antigen, beta domain

C1-setaa 128–209UCSCImmunoglobulin C1-set domain

Gene Aliases

HGNC Name

major histocompatibility complex, class II, DR beta 1

HGNC Previous Symbol

HLA-DR1B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002124.4

p.I177T

c.530T>C

Surrounding Variants

1 paper

NM_002124.4

p.I177I

c.531C>T

1 paper

NM_002124.4

p.L176L

c.528G>T

10 papers

NM_002124.4

p.Q178H

c.534G>T

11 papers

NM_002124.4

p.Q178H

c.534G>C

1 paper

NM_002124.4

p.Q178Q

c.534G>A

1 paper

NM_002124.4

p.T174T

c.522A>G

1 paper

NM_002124.4

p.G180E

c.539G>A

1 paper

NM_002124.4

p.D181H

c.541G>C

1 paper

NM_002124.4

p.D181D

c.543C>T

1 paper

NM_002124.4

p.W182G

c.544T>G

2 papers

NM_002124.4

p.V172V

c.516G>T

2 papers

NM_002124.4

p.T183N

c.548C>A