Varaico: Literature-Extracted Genetic Variants

HLA-DRB1

592 papers

RefSeq Summary

HLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central ...

Pfam Domains

MHC_II_betaaa 42–116UCSCClass II histocompatibility antigen, beta domain

C1-setaa 128–209UCSCImmunoglobulin C1-set domain

Gene Aliases

HGNC Name

major histocompatibility complex, class II, DR beta 1

HGNC Previous Symbol

HLA-DR1B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002124.4

p.G170W

c.508G>T

Surrounding Variants

15 papers

NM_002124.4

p.A169T

c.505G>A

6 papers

NM_002124.4

p.M171V

c.511A>G

1 paper

NM_002124.4

p.K168N

c.504G>T

2 papers

NM_002124.4

p.V172V

c.516G>T

1 paper

NM_002124.4

p.E167*

c.499G>T

1 paper

NM_002124.4

p.E166K

c.496G>A

1 paper

NM_002124.4

p.T174T

c.522A>G

1 paper

NM_002124.4

p.G164V

c.491G>T

1 paper

NM_002124.4

p.G164R

c.490G>C

2 papers

NM_002124.4

p.G164S

c.490G>A

7 papers

NM_002124.4

p.N163N

c.489C>T

1 paper

NM_002124.4

p.N163K

c.489C>G