Varaico: Literature-Extracted Genetic Variants

HLA-DRB1

592 papers

RefSeq Summary

HLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central ...

Pfam Domains

MHC_II_betaaa 42–116UCSCClass II histocompatibility antigen, beta domain

C1-setaa 128–209UCSCImmunoglobulin C1-set domain

Gene Aliases

HGNC Name

major histocompatibility complex, class II, DR beta 1

HGNC Previous Symbol

HLA-DR1B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

8 papers

NM_002124.4

p.T106T

c.318C>T

Surrounding Variants

1 paper

NM_002124.4

p.T106delins

c.317_318delinsAT

1 paper

NM_002124.4

p.Y107D

c.319T>G

1 paper

NM_002124.4

p.T106S

c.317C>G

13 papers

NM_002124.4

p.T106N

c.317C>A

2 papers

NM_002124.4

p.Y107Y

c.321C>T

3 papers

NM_002124.4

p.Y107*

c.321C>G

3 papers

NM_002124.4

p.Y107*

c.321C>A

1 paper

NM_002124.4

p.T106_Y107delins

c.317_321delinsACTAA

1 paper

NM_002124.4

p.C108G

c.322T>G

2 papers

NM_002124.4

p.D105G

c.314A>G

1 paper

NM_002124.4

p.C108F

c.323G>T

1 paper

NM_002124.4

p.D105Y

c.313G>T