Varaico: Literature-Extracted Genetic Variants

HLA-DRB1

592 papers

RefSeq Summary

HLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central ...

Pfam Domains

MHC_II_betaaa 42–116UCSCClass II histocompatibility antigen, beta domain

C1-setaa 128–209UCSCImmunoglobulin C1-set domain

Gene Aliases

HGNC Name

major histocompatibility complex, class II, DR beta 1

HGNC Previous Symbol

HLA-DR1B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

6 papers

NM_002124.4

p.A102G

c.305C>G

Surrounding Variants

1 paper

NM_002124.4

p.A102V

c.305C>T

1 paper

NM_002124.4

p.R101insFs

c.302dupG

3 papers

NM_002124.4

p.R101_A102delFs

c.303_304delCC

1 paper

NM_002124.4

p.A102A

c.306C>G

1 paper

NM_002124.4

p.A102fs

c.304_305fs

1 paper

NM_002124.4

p.A102fs

c.304_305fs

9 papers

NM_002124.4

p.R101fs

c.301_302fs

4 papers

NM_002124.4

p.A103P

c.307G>C

1 paper

NM_002124.4

p.R101R

c.303G>C

2 papers

NM_002124.4

p.A103T

c.307G>A

4 papers

NM_002124.4

p.R101delFs

c.301_302delCG

1 paper

NM_002124.4

p.R101L

c.302G>T