Varaico: Literature-Extracted Genetic Variants

HLA-DRB1

592 papers

RefSeq Summary

HLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central ...

Pfam Domains

MHC_II_betaaa 42–116UCSCClass II histocompatibility antigen, beta domain

C1-setaa 128–209UCSCImmunoglobulin C1-set domain

Gene Aliases

HGNC Name

major histocompatibility complex, class II, DR beta 1

HGNC Previous Symbol

HLA-DR1B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002124.4

p.E88Q

c.262G>C

Surrounding Variants

1 paper

NM_002124.4

p.E88*

c.262G>T

1 paper

NM_002124.4

p.A87A

c.261T>G

2 papers

NM_002124.4

p.A87A

c.261T>C

1 paper

NM_002124.4

p.D86_A87delins

c.257_261delinsTCGCC

2 papers

NM_002124.4

p.E88G

c.263A>G

1 paper

NM_002124.4

p.A87V

c.260C>T

1 paper

NM_002124.4

p.A87G

c.260C>G

2 papers

NM_002124.4

p.A87D

c.260C>A

4 papers

NM_002124.4

p.Y89H

c.265T>C

2 papers

NM_002124.4

p.D86D

c.258C>T

3 papers

NM_002124.4

p.Y89S

c.266A>C

3 papers

NM_002124.4

p.D86V

c.257A>T