Varaico: Literature-Extracted Genetic Variants

HLA-DRB1

592 papers

RefSeq Summary

HLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central ...

Pfam Domains

MHC_II_betaaa 42–116UCSCClass II histocompatibility antigen, beta domain

C1-setaa 128–209UCSCImmunoglobulin C1-set domain

Gene Aliases

HGNC Name

major histocompatibility complex, class II, DR beta 1

HGNC Previous Symbol

HLA-DR1B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002124.4

p.N62K

c.186C>A

Surrounding Variants

1 paper

NM_002124.4

p.N62K

c.186C>G

1 paper

NM_002124.4

p.N62S

c.185A>G

1 paper

NM_002124.4

p.Q63R

c.188A>G

4 papers

NM_002124.4

p.N62H

c.184A>C

2 papers

NM_002124.4

p.Q63Q

c.189G>A

1 paper

NM_002124.4

p.E64K

c.190G>A

8 papers

NM_002124.4

p.Y61H

c.181T>C

1 paper

NM_002124.4

p.E64V

c.191A>T

2 papers

NM_002124.4

p.F60V

c.178T>G

6 papers

NM_002124.4

p.F60I

c.178T>A

1 paper

NM_002124.4

p.E65G

c.194A>G

3 papers

NM_002124.4

p.E65_S66insFs

c.195_196insC