Varaico: Literature-Extracted Genetic Variants

HLA-DRB1

592 papers

RefSeq Summary

HLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central ...

Pfam Domains

MHC_II_betaaa 42–116UCSCClass II histocompatibility antigen, beta domain

C1-setaa 128–209UCSCImmunoglobulin C1-set domain

Gene Aliases

HGNC Name

major histocompatibility complex, class II, DR beta 1

HGNC Previous Symbol

HLA-DR1B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002124.4

p.T32Fs

c.94delinsTGTFs

Surrounding Variants

1 paper

NM_002124.4

p.D31delFs

c.93delG

1 paper

NM_002124.4

p.D31Y

c.91G>T

1 paper

NM_002124.4

p.R33G

c.97C>G

3 papers

NM_002124.4

p.R33R

c.97C>A

1 paper

NM_002124.4

p.G30insFs

c.89_90insGT

3 papers

NM_002124.4

p.R33Q

c.98G>A

2 papers

NM_002124.4

p.P34Splc

c.100+1G>C

1 paper

NM_002124.4

p.P34Splc

c.100+2T>C

7 papers

NM_002124.4

p.S29A

c.85T>G

1 paper

NM_002124.4

p.L28_S29delins

c.84_85delinsCG

7 papers

NM_002124.4

p.L28F

c.84G>T

8 papers

NM_002124.4

p.L28F

c.84G>C