Varaico: Literature-Extracted Genetic Variants

HLA-DRB1

592 papers

RefSeq Summary

HLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central ...

Pfam Domains

MHC_II_betaaa 42–116UCSCClass II histocompatibility antigen, beta domain

C1-setaa 128–209UCSCImmunoglobulin C1-set domain

Gene Aliases

HGNC Name

major histocompatibility complex, class II, DR beta 1

HGNC Previous Symbol

HLA-DR1B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

8 papers

NM_002124.4

p.P25R

c.74C>G

Surrounding Variants

1 paper

NM_002124.4

p.P25T

c.73C>A

1 paper

NM_002124.4

p.S24_P25insFs

c.72_73insC

3 papers

NM_002124.4

p.S24F

c.71C>T

1 paper

NM_002124.4

p.S24Y

c.71C>A

1 paper

NM_002124.4

p.S23_S24insFs

c.69_70insCA

1 paper

NM_002124.4

p.A27S

c.79G>T

1 paper

NM_002124.4

p.A27T

c.79G>A

1 paper

NM_002124.4

p.S23insFs

c.68dupG

1 paper

NM_002124.4

p.S23_S24insFs

c.69_70insA

1 paper

NM_002124.4

p.S23T

c.68G>C

1 paper

NM_002124.4

p.L22L

c.66G>T

2 papers

NM_002124.4

p.L22insFs

c.65_66insG