Varaico: Literature-Extracted Genetic Variants

HLA-DRB1

592 papers

RefSeq Summary

HLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central ...

Pfam Domains

MHC_II_betaaa 42–116UCSCClass II histocompatibility antigen, beta domain

C1-setaa 128–209UCSCImmunoglobulin C1-set domain

Gene Aliases

HGNC Name

major histocompatibility complex, class II, DR beta 1

HGNC Previous Symbol

HLA-DR1B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_002124.4

p.A14_L15delFs

c.42_43delGC

Surrounding Variants

3 papers

NM_002124.4

p.L15L

c.43C>T

5 papers

NM_002124.4

p.A14A

c.42G>T

1 paper

NM_002124.4

p.A14delins

c.41_42delinsTT

1 paper

NM_002124.4

p.T13_A14delins

c.37_42delinsGCAGTT

2 papers

NM_002124.4

p.T13_A14delins

c.37_42delinsGCAGCT

9 papers

NM_002124.4

p.A14V

c.41C>T

1 paper

NM_002124.4

p.T16I

c.47C>T

1 paper

NM_002124.4

p.A14G

c.41C>G

2 papers

NM_002124.4

p.A14P

c.40G>C

1 paper

NM_002124.4

p.A14T

c.40G>A

1 paper

NM_002124.4

p.V17L

c.49G>T

2 papers

NM_002124.4

p.V17_T18insG

c.49_53ins3