Varaico: Literature-Extracted Genetic Variants

HLA-DRB5

201 papers

RefSeq Summary

HLA-DRB5 belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DRA) and a beta (DRB) chain, both anchored in the membrane. It plays a centr...

Pfam Domains

MHC_II_betaaa 42–116UCSCClass II histocompatibility antigen, beta domain

C1-setaa 128–209UCSCImmunoglobulin C1-set domain

Gene Aliases

HGNC Name

major histocompatibility complex, class II, DR beta 5

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_002125.4

p.Q178H

c.534G>C

Surrounding Variants

2 papers

NM_002125.4

p.Q178H

c.534G>T

4 papers

NM_002125.4

p.Q178_N179insCT

c.532_536ins6

2 papers

NM_002125.4

p.I177I

c.531T>C

1 paper

NM_002125.4

p.D181Y

c.541G>T

1 paper

NM_002125.4

p.D181D

c.543C>T

1 paper

NM_002125.4

p.T174T

c.522A>G

2 papers

NM_002125.4

p.V171_V172del2

c.511_515del6

1 paper

NM_002125.4

p.V171G

c.512T>G

2 papers

NM_002125.4

p.T186I

c.557C>T

1 paper

NM_002125.4

p.T186T

c.558C>T

1 paper

NM_002125.4

p.T186T

c.558C>A

1 paper

NM_002125.4

p.T186delins

c.557_558delinsTT