Varaico: Literature-Extracted Genetic Variants

HLA-DRB5

201 papers

RefSeq Summary

HLA-DRB5 belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DRA) and a beta (DRB) chain, both anchored in the membrane. It plays a centr...

Pfam Domains

MHC_II_betaaa 42–116UCSCClass II histocompatibility antigen, beta domain

C1-setaa 128–209UCSCImmunoglobulin C1-set domain

Gene Aliases

HGNC Name

major histocompatibility complex, class II, DR beta 5

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_002125.4

p.D86G

c.257A>G

Surrounding Variants

7 papers

NM_002125.4

p.D86V

c.257A>T

2 papers

NM_002125.4

p.D86N

c.256G>A

1 paper

NM_002125.4

p.D86D

c.258C>T

4 papers

NM_002125.4

p.A87D

c.260C>A

1 paper

NM_002125.4

p.A87A

c.261T>G

1 paper

NM_002125.4

p.A87A

c.261T>C

1 paper

NM_002125.4

p.D86_A87delins

c.258_261delinsTGAG

1 paper

NM_002125.4

p.L82_A87delins

c.246_261delinsAGGGCGGCCTGTCGCC

1 paper

NM_002125.4

p.Y89S

c.266A>C

2 papers

NM_002125.4

p.T80R

c.239C>G

1 paper

NM_002125.4

p.Q93*

c.277C>T

5 papers

NM_002125.4

p.R77Q

c.230G>A