Varaico: Literature-Extracted Genetic Variants

HLA-DRB5

201 papers

RefSeq Summary

HLA-DRB5 belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DRA) and a beta (DRB) chain, both anchored in the membrane. It plays a centr...

Pfam Domains

MHC_II_betaaa 42–116UCSCClass II histocompatibility antigen, beta domain

C1-setaa 128–209UCSCImmunoglobulin C1-set domain

Gene Aliases

HGNC Name

major histocompatibility complex, class II, DR beta 5

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

6 papers

NM_002125.4

p.L67V

c.199T>G

Surrounding Variants

1 paper

NM_002125.4

p.L67insFs

c.199_200insCC

2 papers

NM_002125.4

p.D66_L67delins

c.196_199delinsAACG

4 papers

NM_002125.4

p.L67S

c.200T>C

1 paper

NM_002125.4

p.D66_L67delins

c.196_200delinsTACGC

1 paper

NM_002125.4

p.L67fs

c.199_200fs

2 papers

NM_002125.4

p.D66V

c.197A>T

4 papers

NM_002125.4

p.D66A

c.197A>C

2 papers

NM_002125.4

p.D66insFs

c.197_198insG

4 papers

NM_002125.4

p.D66Y

c.196G>T

1 paper

NM_002125.4

p.D66N

c.196G>A

3 papers

NM_002125.4

p.F69Y

c.206T>A

1 paper

NM_002125.4

p.E64V

c.191A>T