Varaico: Literature-Extracted Genetic Variants

HLA-DRB5

201 papers

RefSeq Summary

HLA-DRB5 belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DRA) and a beta (DRB) chain, both anchored in the membrane. It plays a centr...

Pfam Domains

MHC_II_betaaa 42–116UCSCClass II histocompatibility antigen, beta domain

C1-setaa 128–209UCSCImmunoglobulin C1-set domain

Gene Aliases

HGNC Name

major histocompatibility complex, class II, DR beta 5

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002125.4

p.F55L

c.163T>C

Surrounding Variants

5 papers

NM_002125.4

p.F55I

c.163T>A

1 paper

NM_002125.4

p.F55Y

c.164T>A

2 papers

NM_002125.4

p.R54Q

c.161G>A

1 paper

NM_002125.4

p.F55L

c.165C>G

1 paper

NM_002125.4

p.F55L

c.165C>A

1 paper

NM_002125.4

p.F55delins

c.164_165delinsAT

5 papers

NM_002125.4

p.R54W

c.160C>T

3 papers

NM_002125.4

p.H57D

c.169C>G

5 papers

NM_002125.4

p.H57N

c.169C>A

1 paper

NM_002125.4

p.H57fs

c.169_170fs

1 paper

NM_002125.4

p.R52R

c.156G>A

5 papers

NM_002125.4

p.H57L

c.170A>T