Varaico: Literature-Extracted Genetic Variants

Gene:HMGB1
Variant:p.Y155delFs

HMGB1

211 papers

RefSeq Summary

This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DN...

Pfam Domains

HMG_box_2aa 6–79UCSCHMG-box domain
HMG_boxaa 95–163UCSCHMG (high mobility group) box

Gene Aliases

HGNC Name

high mobility group box 1

HGNC Previous Symbol

HMG1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_002128.7
p.Y155delFs
c.465delA
Surrounding Variants
3 papers
NM_002128.7
p.E156Q
c.466G>C
2 papers
NM_002128.7
p.Y155S
c.464A>C
1 paper
NM_002128.7
p.K154N
c.462A>C
1 paper
NM_002128.7
p.K157K
c.471G>A
2 papers
NM_002128.7
p.K152E
c.454A>G
1 paper
NM_002128.7
p.A149V
c.446C>T
4 papers
NM_002128.7
p.A149E
c.446C>A
1 paper
NM_002128.7
p.A149T
c.445G>A
1 paper
NM_002128.7
p.K147fs
c.439_440fs
1 paper
NM_002128.7
p.K146N
c.438G>T
2 papers
NM_002128.7
p.K146insFs
c.437dupA
1 paper
NM_002128.7
p.K146N
c.438G>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."