high mobility group nucleosomal binding domain 3

TRIP7

thyroid hormone receptor interactor 7

High mobility group nucleosome-binding domain-containing protein 3

Thyroid receptor-interacting protein 7

TR-interacting protein 7

TRIP-7

The protein encoded by this gene binds thyroid hormone receptor beta in the presence of thyroid hormone. The encoded protein, a member of the HMGN protein family, is thought to reduce the compactness of the chromatin fiber in nucleosomes, thereby enhancing transcription from chromatin templates. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. There is a related pseudogene on chromosome 1. [provided by RefSeq, Jan 2016].

Varaico: Literature-Extracted Genetic Variants

HMGN3

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Previous Symbol