Varaico: Literature-Extracted Genetic Variants

Gene:HNMT
Variant:p.M36T

HNMT

182 papers

RefSeq Summary

In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which...

Pfam Domains

Methyltransf_23aa 32–218UCSCMethyltransferase domain

Gene Aliases

HGNC Name

histamine N-methyltransferase

HGNC Alias Symbol

HMT

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_006895.3
p.M36T
c.107T>C
Surrounding Variants
1 paper
NM_006895.3
p.K39E
c.115A>G
3 papers
NM_006895.3
p.Q30*
c.88C>T
1 paper
NM_006895.3
p.G42G
c.126C>T
1 paper
NM_006895.3
p.Y15*
c.45T>A
1 paper
NM_006895.3
p.K14T
c.41A>C
1 paper
NM_006895.3
p.K14R
c.41A>G
1 paper
NM_006895.3
p.D11D
c.33C>T
1 paper
NM_006895.3
p.S10T
c.28T>A
1 paper
NM_006895.3
p.M5T
c.14T>C
1 paper
NM_006895.3
p.I59T
c.176T>C
1 paper
NM_006895.3
p.G60R
c.178G>C
6 papers
NM_006895.3
p.G60D
c.179G>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."