Varaico: Literature-Extracted Genetic Variants

HPGDS

1,322 papers

RefSeq Summary

Prostaglandin-D synthase is a sigma class glutathione-S-transferase family member. The enzyme catalyzes the conversion of PGH2 to PGD2 and plays a role in the production of prostanoids in the immune s...

Pfam Domains

GST_Naa 4–73UCSCGlutathione S-transferase, N-terminal domain

GST_C_3aa 92–194UCSCGlutathione S-transferase, C-terminal domain

Gene Aliases

HGNC Name

hematopoietic prostaglandin D synthase

HGNC Alias Symbols

GSTS; PGDS; H-PGDS; PGD2; GSTS1-1; GSTS1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014485.3

p.T197S

c.590C>G

Surrounding Variants

1 paper

NM_014485.3

p.T197I

c.590C>T

1 paper

NM_014485.3

p.T197S

c.589A>T

2 papers

NM_014485.3

p.T197A

c.589A>G

2 papers

NM_014485.3

p.K198E

c.592A>G

1 paper

NM_014485.3

p.K198R

c.593A>G

2 papers

NM_014485.3

p.K198N

c.594A>T

2 papers

NM_014485.3

p.K198N

c.594A>C

2 papers

NM_014485.3

p.L199F

c.595C>T

1 paper

NM_014485.3

p.L199I

c.595C>A

1 paper

NM_014485.3

p.P195R

c.584C>G

2 papers

NM_014485.3

p.L199L

c.597C>G

1 paper

NM_014485.3

p.*200K

c.598T>A