Varaico: Literature-Extracted Genetic Variants

HPGDS

1,322 papers

RefSeq Summary

Prostaglandin-D synthase is a sigma class glutathione-S-transferase family member. The enzyme catalyzes the conversion of PGH2 to PGD2 and plays a role in the production of prostanoids in the immune s...

Pfam Domains

GST_Naa 4–73UCSCGlutathione S-transferase, N-terminal domain

GST_C_3aa 92–194UCSCGlutathione S-transferase, C-terminal domain

Gene Aliases

HGNC Name

hematopoietic prostaglandin D synthase

HGNC Alias Symbols

GSTS; PGDS; H-PGDS; PGD2; GSTS1-1; GSTS1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014485.3

p.A183_A186del4

c.547_557del12

Surrounding Variants

3 papers

NM_014485.3

p.V187I

c.559G>A

1 paper

NM_014485.3

p.V187V

c.561C>T

1 paper

NM_014485.3

p.A186A

c.558C>T

1 paper

NM_014485.3

p.A188V

c.563C>T

2 papers

NM_014485.3

p.K192R

c.575A>G

1 paper

NM_014485.3

p.R193*

c.577C>T

1 paper

NM_014485.3

p.R193Q

c.578G>A

1 paper

NM_014485.3

p.R193R

c.579A>T

8 papers

NM_014485.3

p.R194W

c.580A>T

1 paper

NM_014485.3

p.K180R

c.539A>G

1 paper

NM_014485.3

p.K179_K180insFs

c.537_538insC

1 paper

NM_014485.3

p.P195R

c.584C>G