Varaico: Literature-Extracted Genetic Variants

HPGDS

1,322 papers

RefSeq Summary

Prostaglandin-D synthase is a sigma class glutathione-S-transferase family member. The enzyme catalyzes the conversion of PGH2 to PGD2 and plays a role in the production of prostanoids in the immune s...

Pfam Domains

GST_Naa 4–73UCSCGlutathione S-transferase, N-terminal domain

GST_C_3aa 92–194UCSCGlutathione S-transferase, C-terminal domain

Gene Aliases

HGNC Name

hematopoietic prostaglandin D synthase

HGNC Alias Symbols

GSTS; PGDS; H-PGDS; PGD2; GSTS1-1; GSTS1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014485.3

p.R178W

c.532C>T

Surrounding Variants

1 paper

NM_014485.3

p.R178P

c.533G>C

1 paper

NM_014485.3

p.L177*

c.530T>A

1 paper

NM_014485.3

p.L177V

c.529T>G

1 paper

NM_014485.3

p.K179Q

c.535A>C

1 paper

NM_014485.3

p.T176T

c.528T>A

2 papers

NM_014485.3

p.K179M

c.536A>T

1 paper

NM_014485.3

p.K179_K180insFs

c.537_538insC

1 paper

NM_014485.3

p.T176S

c.527C>G

1 paper

NM_014485.3

p.T176S

c.526A>T

1 paper

NM_014485.3

p.T176P

c.526A>C

1 paper

NM_014485.3

p.K180R

c.539A>G

1 paper

NM_014485.3

p.V175A

c.524T>C