Varaico: Literature-Extracted Genetic Variants

HPGDS

1,322 papers

RefSeq Summary

Prostaglandin-D synthase is a sigma class glutathione-S-transferase family member. The enzyme catalyzes the conversion of PGH2 to PGD2 and plays a role in the production of prostanoids in the immune s...

Pfam Domains

GST_Naa 4–73UCSCGlutathione S-transferase, N-terminal domain

GST_C_3aa 92–194UCSCGlutathione S-transferase, C-terminal domain

Gene Aliases

HGNC Name

hematopoietic prostaglandin D synthase

HGNC Alias Symbols

GSTS; PGDS; H-PGDS; PGD2; GSTS1-1; GSTS1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

5 papers

NM_014485.3

p.H171Y

c.511C>T

Surrounding Variants

1 paper

NM_014485.3

p.D169N

c.505G>A

2 papers

NM_014485.3

p.R173W

c.517A>T

1 paper

NM_014485.3

p.R173K

c.518G>A

2 papers

NM_014485.3

p.R173S

c.519G>T

2 papers

NM_014485.3

p.R173S

c.519G>C

1 paper

NM_014485.3

p.L174R

c.521T>G

2 papers

NM_014485.3

p.L174P

c.521T>C

1 paper

NM_014485.3

p.L167Q

c.500T>A

1 paper

NM_014485.3

p.L174L

c.522G>A

1 paper

NM_014485.3

p.V175A

c.524T>C

2 papers

NM_014485.3

p.D166E

c.498C>G

1 paper

NM_014485.3

p.D166E

c.498C>A