Varaico: Literature-Extracted Genetic Variants

HPGDS

1,322 papers

RefSeq Summary

Prostaglandin-D synthase is a sigma class glutathione-S-transferase family member. The enzyme catalyzes the conversion of PGH2 to PGD2 and plays a role in the production of prostanoids in the immune s...

Pfam Domains

GST_Naa 4–73UCSCGlutathione S-transferase, N-terminal domain

GST_C_3aa 92–194UCSCGlutathione S-transferase, C-terminal domain

Gene Aliases

HGNC Name

hematopoietic prostaglandin D synthase

HGNC Alias Symbols

GSTS; PGDS; H-PGDS; PGD2; GSTS1-1; GSTS1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014485.3

p.V146I

c.436G>A

Surrounding Variants

1 paper

NM_014485.3

p.T147S

c.439A>T

1 paper

NM_014485.3

p.T147A

c.439A>G

1 paper

NM_014485.3

p.T147S

c.440C>G

1 paper

NM_014485.3

p.T147delFs

c.439delT

1 paper

NM_014485.3

p.T147T

c.441T>C

2 papers

NM_014485.3

p.A149P

c.445G>C

2 papers

NM_014485.3

p.D150Y

c.448G>T

4 papers

NM_014485.3

p.D150A

c.449A>C

1 paper

NM_014485.3

p.D150E

c.450C>A

1 paper

NM_014485.3

p.F151L

c.451T>C

1 paper

NM_014485.3

p.F151L

c.453C>G

1 paper

NM_014485.3

p.F151L

c.453C>A