Varaico: Literature-Extracted Genetic Variants

HPGDS

1,322 papers

RefSeq Summary

Prostaglandin-D synthase is a sigma class glutathione-S-transferase family member. The enzyme catalyzes the conversion of PGH2 to PGD2 and plays a role in the production of prostanoids in the immune s...

Pfam Domains

GST_Naa 4–73UCSCGlutathione S-transferase, N-terminal domain

GST_C_3aa 92–194UCSCGlutathione S-transferase, C-terminal domain

Gene Aliases

HGNC Name

hematopoietic prostaglandin D synthase

HGNC Alias Symbols

GSTS; PGDS; H-PGDS; PGD2; GSTS1-1; GSTS1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_014485.3

p.K112E

c.334A>G

Surrounding Variants

3 papers

NM_014485.3

p.K112*

c.334A>T

1 paper

NM_014485.3

p.V111V

c.333G>C

1 paper

NM_014485.3

p.K112R

c.335A>G

1 paper

NM_014485.3

p.V111A

c.332T>C

1 paper

NM_014485.3

p.K112_E113Splc

c.336+1G>C

1 paper

NM_014485.3

p.K112_E113Splc

c.336+2T>C

2 papers

NM_014485.3

p.D110G

c.329A>G

1 paper

NM_014485.3

p.D110A

c.329A>C

1 paper

NM_014485.3

p.D110insFs

c.328_329insC

2 papers

NM_014485.3

p.D110N

c.328G>A

1 paper

NM_014485.3

p.Q109_D110insFs

c.327_328insC

1 paper

NM_014485.3

p.K108K

c.324G>A