Varaico: Literature-Extracted Genetic Variants

HPGDS

1,322 papers

RefSeq Summary

Prostaglandin-D synthase is a sigma class glutathione-S-transferase family member. The enzyme catalyzes the conversion of PGH2 to PGD2 and plays a role in the production of prostanoids in the immune s...

Pfam Domains

GST_Naa 4–73UCSCGlutathione S-transferase, N-terminal domain

GST_C_3aa 92–194UCSCGlutathione S-transferase, C-terminal domain

Gene Aliases

HGNC Name

hematopoietic prostaglandin D synthase

HGNC Alias Symbols

GSTS; PGDS; H-PGDS; PGD2; GSTS1-1; GSTS1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014485.3

p.Y70C

c.209A>G

Surrounding Variants

1 paper

NM_014485.3

p.Y70*

c.210T>A

2 papers

NM_014485.3

p.L71*

c.212T>A

2 papers

NM_014485.3

p.R69G

c.205A>G

1 paper

NM_014485.3

p.T72S

c.214A>T

1 paper

NM_014485.3

p.T72S

c.215C>G

1 paper

NM_014485.3

p.K73E

c.217A>G

1 paper

NM_014485.3

p.K73Q

c.217A>C

1 paper

NM_014485.3

p.K73I

c.218A>T

1 paper

NM_014485.3

p.A66A

c.198A>G

1 paper

NM_014485.3

p.L65R

c.194T>G

1 paper

NM_014485.3

p.T75K

c.224C>A

1 paper

NM_014485.3

p.L65I

c.193C>A