Varaico: Literature-Extracted Genetic Variants

HPGDS

1,322 papers

RefSeq Summary

Prostaglandin-D synthase is a sigma class glutathione-S-transferase family member. The enzyme catalyzes the conversion of PGH2 to PGD2 and plays a role in the production of prostanoids in the immune s...

Pfam Domains

GST_Naa 4–73UCSCGlutathione S-transferase, N-terminal domain

GST_C_3aa 92–194UCSCGlutathione S-transferase, C-terminal domain

Gene Aliases

HGNC Name

hematopoietic prostaglandin D synthase

HGNC Alias Symbols

GSTS; PGDS; H-PGDS; PGD2; GSTS1-1; GSTS1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014485.3

p.G58*

c.172G>T

Surrounding Variants

1 paper

NM_014485.3

p.G58Fs

c.172_173delinsTTAFs

2 papers

NM_014485.3

p.D57A

c.170A>C

1 paper

NM_014485.3

p.V56V

c.168T>G

1 paper

NM_014485.3

p.V56G

c.167T>G

2 papers

NM_014485.3

p.V56D

c.167T>A

1 paper

NM_014485.3

p.V56I

c.166G>A

1 paper

NM_014485.3

p.T60S

c.178A>T

1 paper

NM_014485.3

p.T60S

c.179C>G

1 paper

NM_014485.3

p.E55D

c.165A>T

1 paper

NM_014485.3

p.E55D

c.165A>C

1 paper

NM_014485.3

p.T60T

c.180T>A

3 papers

NM_014485.3

p.E55A

c.164A>C