Varaico: Literature-Extracted Genetic Variants

HPGDS

1,322 papers

RefSeq Summary

Prostaglandin-D synthase is a sigma class glutathione-S-transferase family member. The enzyme catalyzes the conversion of PGH2 to PGD2 and plays a role in the production of prostanoids in the immune s...

Pfam Domains

GST_Naa 4–73UCSCGlutathione S-transferase, N-terminal domain

GST_C_3aa 92–194UCSCGlutathione S-transferase, C-terminal domain

Gene Aliases

HGNC Name

hematopoietic prostaglandin D synthase

HGNC Alias Symbols

GSTS; PGDS; H-PGDS; PGD2; GSTS1-1; GSTS1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014485.3

p.L46R

c.137T>G

Surrounding Variants

1 paper

NM_014485.3

p.L46P

c.137T>C

1 paper

NM_014485.3

p.L46V

c.136C>G

1 paper

NM_014485.3

p.L46L

c.138C>A

1 paper

NM_014485.3

p.L46I

c.136C>A

2 papers

NM_014485.3

p.P47S

c.139C>T

1 paper

NM_014485.3

p.T45N

c.134C>A

2 papers

NM_014485.3

p.F48Y

c.143T>A

2 papers

NM_014485.3

p.G49R

c.145G>C

2 papers

NM_014485.3

p.G49R

c.145G>A

1 paper

NM_014485.3

p.K50*

c.148A>T

2 papers

NM_014485.3

p.K50Q

c.148A>C

1 paper

NM_014485.3

p.K50I

c.149A>T