Varaico: Literature-Extracted Genetic Variants

HPGDS

1,322 papers

RefSeq Summary

Prostaglandin-D synthase is a sigma class glutathione-S-transferase family member. The enzyme catalyzes the conversion of PGH2 to PGD2 and plays a role in the production of prostanoids in the immune s...

Pfam Domains

GST_Naa 4–73UCSCGlutathione S-transferase, N-terminal domain

GST_C_3aa 92–194UCSCGlutathione S-transferase, C-terminal domain

Gene Aliases

HGNC Name

hematopoietic prostaglandin D synthase

HGNC Alias Symbols

GSTS; PGDS; H-PGDS; PGD2; GSTS1-1; GSTS1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_014485.3

p.R19R

c.57T>G

Surrounding Variants

1 paper

NM_014485.3

p.Y20N

c.58T>A

1 paper

NM_014485.3

p.R19C

c.55C>T

1 paper

NM_014485.3

p.Y20C

c.59A>G

1 paper

NM_014485.3

p.Y20S

c.59A>C

1 paper

NM_014485.3

p.I18I

c.54T>C

1 paper

NM_014485.3

p.I18I

c.54T>A

1 paper

NM_014485.3

p.I21L

c.61A>T

1 paper

NM_014485.3

p.I21V

c.61A>G

1 paper

NM_014485.3

p.R19_Y20delFs

c.57_60del4

1 paper

NM_014485.3

p.R19_Y20del0

c.55_60del6

1 paper

NM_014485.3

p.I17_Y20delFs

c.51_60del10

1 paper

NM_014485.3

p.I21K

c.62T>A