Varaico: Literature-Extracted Genetic Variants

Gene:HSF1
Variant:p.P301L

HSF1

220 papers

RefSeq Summary

The product of this gene is a transcription factor that is rapidly induced after temperature stress and binds heat shock promoter elements (HSE). This protein plays a role in the regulation of lifespa...

Pfam Domains

HSF_DNA-bindaa 18–118UCSCHSF-type DNA-binding
Vert_HS_TFaa 247–529UCSCVertebrate heat shock transcription factor

Gene Aliases

HGNC Name

heat shock transcription factor 1

HGNC Alias Symbol

HSTF1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_005526.4
p.P301L
c.902C>T
Surrounding Variants
1 paper
NM_005526.4
p.P301S
c.901C>T
1 paper
NM_005526.4
p.E300A
c.899A>C
1 paper
NM_005526.4
p.E300Q
c.898G>C
1 paper
NM_005526.4
p.E299A
c.896A>C
1 paper
NM_005526.4
p.K298N
c.894G>C
1 paper
NM_005526.4
p.K298N
c.894G>T
1 paper
NM_005526.4
p.K298Q
c.892A>C
1 paper
NM_005526.4
p.V297A
c.890T>C
1 paper
NM_005526.4
p.S292N
c.875G>A
1 paper
NM_005526.4
p.E311A
c.932A>C
1 paper
NM_005526.4
p.R287S
c.861G>C
1 paper
NM_005526.4
p.R287Splc
c.861-1G>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."