Varaico: Literature-Extracted Genetic Variants

Gene:HTR1B
Variant:p.I367V

HTR1B

361 papers

RefSeq Summary

The protein encoded by this intronless gene is a G-protein coupled receptor for serotonin (5-hydroxytryptamine). Ligand binding activates second messengers that inhibit the activity of adenylate cycla...

Pfam Domains

7tm_1aa 66–369UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

5-hydroxytryptamine receptor 1B

HGNC Alias Symbols

S12; 5-HT1B; HTR1D2; 5-HT1DB

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
5 papers
NM_000863.3
p.I367V
c.1099A>G
Surrounding Variants
2 papers
NM_000863.3
p.I368T
c.1103T>C
1 paper
NM_000863.3
p.T370N
c.1109C>A
1 paper
NM_000863.3
p.N373D
c.1117A>G
1 paper
NM_000863.3
p.N373K
c.1119T>G
1 paper
NM_000863.3
p.N373K
c.1119T>A
5 papers
NM_000863.3
p.E374K
c.1120G>A
1 paper
NM_000863.3
p.Y359*
c.1077T>A
1 paper
NM_000863.3
p.Y359S
c.1076A>C
1 paper
NM_000863.3
p.G358D
c.1073G>A
1 paper
NM_000863.3
p.R385C
c.1153C>T
1 paper
NM_000863.3
p.C340S
c.1019G>C
1 paper
NM_000863.3
p.S334A
c.1000T>G
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."