Varaico: Literature-Extracted Genetic Variants

Gene:HTR1B
Variant:p.R310H

HTR1B

361 papers

RefSeq Summary

The protein encoded by this intronless gene is a G-protein coupled receptor for serotonin (5-hydroxytryptamine). Ligand binding activates second messengers that inhibit the activity of adenylate cycla...

Pfam Domains

7tm_1aa 66–369UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

5-hydroxytryptamine receptor 1B

HGNC Alias Symbols

S12; 5-HT1B; HTR1D2; 5-HT1DB

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000863.3
p.R310H
c.929G>A
Surrounding Variants
1 paper
NM_000863.3
p.K314K
c.942G>A
1 paper
NM_000863.3
p.T315I
c.944C>T
1 paper
NM_000863.3
p.I318V
c.952A>G
1 paper
NM_000863.3
p.I318N
c.953T>A
1 paper
NM_000863.3
p.K302M
c.905A>T
1 paper
NM_000863.3
p.G321R
c.961G>C
1 paper
NM_000863.3
p.V325M
c.973G>A
1 paper
NM_000863.3
p.W327*
c.980G>A
1 paper
NM_000863.3
p.W327*
c.981G>A
1 paper
NM_000863.3
p.V290A
c.869T>C
1 paper
NM_000863.3
p.V287V
c.861G>T
142 papers
NM_000863.3
p.V287V
c.861G>C
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