Varaico: Literature-Extracted Genetic Variants

Gene:HTR1B
Variant:p.V274I

HTR1B

361 papers

RefSeq Summary

The protein encoded by this intronless gene is a G-protein coupled receptor for serotonin (5-hydroxytryptamine). Ligand binding activates second messengers that inhibit the activity of adenylate cycla...

Pfam Domains

7tm_1aa 66–369UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

5-hydroxytryptamine receptor 1B

HGNC Alias Symbols

S12; 5-HT1B; HTR1D2; 5-HT1DB

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000863.3
p.V274I
c.820G>A
Surrounding Variants
1 paper
NM_000863.3
p.V274A
c.821T>C
1 paper
NM_000863.3
p.R273R
c.819G>A
2 papers
NM_000863.3
p.S272S
c.816G>C
1 paper
NM_000863.3
p.S272S
c.816G>A
1 paper
NM_000863.3
p.V267A
c.800T>C
1 paper
NM_000863.3
p.G282*
c.844G>T
1 paper
NM_000863.3
p.G282E
c.845G>A
1 paper
NM_000863.3
p.S283P
c.847T>C
1 paper
NM_000863.3
p.S263P
c.787T>C
1 paper
NM_000863.3
p.V287A
c.860T>C
1 paper
NM_000863.3
p.V287V
c.861G>T
142 papers
NM_000863.3
p.V287V
c.861G>C
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