Varaico: Literature-Extracted Genetic Variants

Gene:HTR1B
Variant:p.T258A

HTR1B

361 papers

RefSeq Summary

The protein encoded by this intronless gene is a G-protein coupled receptor for serotonin (5-hydroxytryptamine). Ligand binding activates second messengers that inhibit the activity of adenylate cycla...

Pfam Domains

7tm_1aa 66–369UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

5-hydroxytryptamine receptor 1B

HGNC Alias Symbols

S12; 5-HT1B; HTR1D2; 5-HT1DB

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
3 papers
NM_000863.3
p.T258A
c.772A>G
Surrounding Variants
1 paper
NM_000863.3
p.I257M
c.771A>G
1 paper
NM_000863.3
p.I257T
c.770T>C
1 paper
NM_000863.3
p.T258T
c.774C>T
1 paper
NM_000863.3
p.S263P
c.787T>C
1 paper
NM_000863.3
p.V267A
c.800T>C
1 paper
NM_000863.3
p.G248G
c.744C>T
2 papers
NM_000863.3
p.S272S
c.816G>C
1 paper
NM_000863.3
p.S272S
c.816G>A
1 paper
NM_000863.3
p.T243M
c.728C>T
1 paper
NM_000863.3
p.R273R
c.819G>A
1 paper
NM_000863.3
p.V274I
c.820G>A
1 paper
NM_000863.3
p.V274A
c.821T>C
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