Varaico: Literature-Extracted Genetic Variants

Gene:HTR1B
Variant:p.Y218S

HTR1B

361 papers

RefSeq Summary

The protein encoded by this intronless gene is a G-protein coupled receptor for serotonin (5-hydroxytryptamine). Ligand binding activates second messengers that inhibit the activity of adenylate cycla...

Pfam Domains

7tm_1aa 66–369UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

5-hydroxytryptamine receptor 1B

HGNC Alias Symbols

S12; 5-HT1B; HTR1D2; 5-HT1DB

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000863.3
p.Y218S
c.653A>C
Surrounding Variants
1 paper
NM_000863.3
p.Y218C
c.653A>G
4 papers
NM_000863.3
p.F219L
c.655T>C
2 papers
NM_000863.3
p.F219L
c.657C>G
2 papers
NM_000863.3
p.F219L
c.657C>A
1 paper
NM_000863.3
p.P220P
c.660C>G
2 papers
NM_000863.3
p.T221N
c.662C>A
1 paper
NM_000863.3
p.G215C
c.643G>T
1 paper
NM_000863.3
p.L222P
c.665T>C
1 paper
NM_000863.3
p.T213M
c.638C>T
1 paper
NM_000863.3
p.S212F
c.635C>T
1 paper
NM_000863.3
p.S212A
c.634T>G
1 paper
NM_000863.3
p.I225T
c.674T>C
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