Varaico: Literature-Extracted Genetic Variants

Gene:HTR1B
Variant:p.L91M

HTR1B

361 papers

RefSeq Summary

The protein encoded by this intronless gene is a G-protein coupled receptor for serotonin (5-hydroxytryptamine). Ligand binding activates second messengers that inhibit the activity of adenylate cycla...

Pfam Domains

7tm_1aa 66–369UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

5-hydroxytryptamine receptor 1B

HGNC Alias Symbols

S12; 5-HT1B; HTR1D2; 5-HT1DB

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000863.3
p.L91M
c.271C>A
Surrounding Variants
1 paper
NM_000863.3
p.L91P
c.272T>C
1 paper
NM_000863.3
p.S90Y
c.269C>A
3 papers
NM_000863.3
p.A89A
c.267C>T
2 papers
NM_000863.3
p.A92A
c.276G>A
1 paper
NM_000863.3
p.A89V
c.266C>T
1 paper
NM_000863.3
p.I88insFs
c.263_264insCC
2 papers
NM_000863.3
p.L87L
c.261G>T
1 paper
NM_000863.3
p.L87L
c.261G>A
4 papers
NM_000863.3
p.T94T
c.282C>T
1 paper
NM_000863.3
p.V98L
c.292G>T
1 paper
NM_000863.3
p.V98L
c.292G>C
1 paper
NM_000863.3
p.L80Q
c.239T>A
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