Varaico: Literature-Extracted Genetic Variants

ICAM1

914 papers

RefSeq Summary

This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also ...

Pfam Domains

ICAM_Naa 24–115UCSCIntercellular adhesion molecule (ICAM), N-terminal domain

ICAM1_3_5_D2aa 219–308UCSCICAM-1/3/5, D2 domain

Ig_2aa 312–392UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

intercellular adhesion molecule 1

HGNC Alias Symbols

BB2; CD54

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000201.3

p.E165K

c.493G>A

Surrounding Variants

1 paper

NM_000201.3

p.E165G

c.494A>G

1 paper

NM_000201.3

p.P166fs

c.496_497fs

1 paper

NM_000201.3

p.P166_A167delFs

c.498_501del4

1 paper

NM_000201.3

p.A167T

c.499G>A

1 paper

NM_000201.3

p.A167P

c.499G>C

2 papers

NM_000201.3

p.E168Q

c.502G>C

3 papers

NM_000201.3

p.T170M

c.509C>T

1 paper

NM_000201.3

p.R159W

c.475C>T

5 papers

NM_000201.3

p.L157L

c.469C>T

3 papers

NM_000201.3

p.K155N

c.465G>C

3 papers

NM_000201.3

p.K155N

c.465G>T

1 paper

NM_000201.3

p.V175_R176insFs

c.525_526ins7