Varaico: Literature-Extracted Genetic Variants

ICAM1

914 papers

RefSeq Summary

This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also ...

Pfam Domains

ICAM_Naa 24–115UCSCIntercellular adhesion molecule (ICAM), N-terminal domain

ICAM1_3_5_D2aa 219–308UCSCICAM-1/3/5, D2 domain

Ig_2aa 312–392UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

intercellular adhesion molecule 1

HGNC Alias Symbols

BB2; CD54

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000201.3

p.A312S

c.934G>T

Surrounding Variants

2 papers

NM_000201.3

p.V315M

c.943G>A

1 paper

NM_000201.3

p.S309delFs

c.926delG

1 paper

NM_000201.3

p.I316V

c.946A>G

1 paper

NM_000201.3

p.L317insFs

c.949_950insC

1 paper

NM_000201.3

p.L317insFs

c.949_950insA

2 papers

NM_000201.3

p.T318M

c.953C>T

3 papers

NM_000201.3

p.T318T

c.954G>C

1 paper

NM_000201.3

p.K319R

c.956A>G

1 paper

NM_000201.3

p.G325delFs

c.974delG

1 paper

NM_000201.3

p.G325R

c.973G>A

1 paper

NM_000201.3

p.H335Y

c.1003C>T

1 paper

NM_000201.3

p.H335P

c.1004A>C