Varaico: Literature-Extracted Genetic Variants

ICAM1

914 papers

RefSeq Summary

This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also ...

Pfam Domains

ICAM_Naa 24–115UCSCIntercellular adhesion molecule (ICAM), N-terminal domain

ICAM1_3_5_D2aa 219–308UCSCICAM-1/3/5, D2 domain

Ig_2aa 312–392UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

intercellular adhesion molecule 1

HGNC Alias Symbols

BB2; CD54

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000201.3

p.D364H

c.1090G>C

Surrounding Variants

2 papers

NM_000201.3

p.D364A

c.1091A>C

1 paper

NM_000201.3

p.E363A

c.1088A>C

3 papers

NM_000201.3

p.R367C

c.1099C>T

1 paper

NM_000201.3

p.R367R

c.1101C>A

1 paper

NM_000201.3

p.F369_S370del2

c.1105_1109del6

1 paper

NM_000201.3

p.K359E

c.1075A>G

1 paper

NM_000201.3

p.S370C

c.1109C>G

1 paper

NM_000201.3

p.T374insFs

c.1122dupC

2 papers

NM_000201.3

p.R353S

c.1059G>C

9 papers

NM_000201.3

p.P352L

c.1055C>T

1 paper

NM_000201.3

p.L381insFs

c.1142dupT

1 paper

NM_000201.3

p.L381fs

c.1141_1142fs