Varaico: Literature-Extracted Genetic Variants

ICAM1

914 papers

RefSeq Summary

This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also ...

Pfam Domains

ICAM_Naa 24–115UCSCIntercellular adhesion molecule (ICAM), N-terminal domain

ICAM1_3_5_D2aa 219–308UCSCICAM-1/3/5, D2 domain

Ig_2aa 312–392UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

intercellular adhesion molecule 1

HGNC Alias Symbols

BB2; CD54

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000201.3

p.S461G

c.1381A>G

Surrounding Variants

3 papers

NM_000201.3

p.R458W

c.1372C>T

1 paper

NM_000201.3

p.E465D

c.1395G>T

1 paper

NM_000201.3

p.T467I

c.1400C>T

1 paper

NM_000201.3

p.T467T

c.1401C>T

1 paper

NM_000201.3

p.R468L

c.1403G>T

1 paper

NM_000201.3

p.R468_K469insFs

c.1404_1405insG

1 paper

NM_000201.3

p.K469insFs

c.1405_1406insG

266 papers

NM_000201.3

p.K469E

c.1405A>G

1 paper

NM_000201.3

p.K469R

c.1406A>G

1 paper

NM_000201.3

p.N473fs

c.1417_1418fs

1 paper

NM_000201.3

p.V474M

c.1420G>A

1 paper

NM_000201.3

p.L475F

c.1423C>T