Varaico: Literature-Extracted Genetic Variants

ICAM1

914 papers

RefSeq Summary

This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also ...

Pfam Domains

ICAM_Naa 24–115UCSCIntercellular adhesion molecule (ICAM), N-terminal domain

ICAM1_3_5_D2aa 219–308UCSCICAM-1/3/5, D2 domain

Ig_2aa 312–392UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

intercellular adhesion molecule 1

HGNC Alias Symbols

BB2; CD54

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000201.3

p.I483V

c.1447A>G

Surrounding Variants

1 paper

NM_000201.3

p.V482A

c.1445T>C

1 paper

NM_000201.3

p.Y479N

c.1435T>A

1 paper

NM_000201.3

p.R478Q

c.1433G>A

10 papers

NM_000201.3

p.R478W

c.1432C>T

3 papers

NM_000201.3

p.A488T

c.1462G>A

1 paper

NM_000201.3

p.M493V

c.1477A>G

3 papers

NM_000201.3

p.A496T

c.1486G>A

1 paper

NM_000201.3

p.L498_Y501del4

c.1492_1502del12

1 paper

NM_000201.3

p.T500M

c.1499C>T

1 paper

NM_000201.3

p.Q506_I509delFs

c.1517_1527del11

1 paper

NM_000201.3

p.R507W

c.1519C>T

1 paper

NM_000201.3

p.K508M

c.1523A>T