Varaico: Literature-Extracted Genetic Variants

Gene:ICOS
Variant:p.F11L

ICOS

156 papers

RefSeq Summary

The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation o...

Pfam Domains

V-set_2aa 23–134UCSCICOS V-set domain

Gene Aliases

HGNC Name

inducible T cell costimulator

HGNC Alias Symbols

AILIM; CD278

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_012092.4
p.F11L
c.31T>C
Surrounding Variants
1 paper
NM_012092.4
p.L10L
c.30C>T
1 paper
NM_012092.4
p.F11L
c.33C>A
1 paper
NM_012092.4
p.F11L
c.33C>G
1 paper
NM_012092.4
p.L10F
c.28C>T
1 paper
NM_012092.4
p.R14C
c.40C>T
1 paper
NM_012092.4
p.R14H
c.41G>A
1 paper
NM_012092.4
p.Y7H
c.19T>C
1 paper
NM_012092.4
p.I15T
c.44T>C
1 paper
NM_012092.4
p.W6delFs
c.18delG
3 papers
NM_012092.4
p.V17I
c.49G>A
2 papers
NM_012092.4
p.T19I
c.56C>T
1 paper
NM_012092.4
p.K2delFs
c.6delG
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."