Varaico: Literature-Extracted Genetic Variants

Gene:ICOS
Variant:p.G59insFs

ICOS

156 papers

RefSeq Summary

The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation o...

Pfam Domains

V-set_2aa 23–134UCSCICOS V-set domain

Gene Aliases

HGNC Name

inducible T cell costimulator

HGNC Alias Symbols

AILIM; CD278

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_012092.4
p.G59insFs
c.177dupG
Surrounding Variants
1 paper
NM_012092.4
p.G58R
c.172G>A
1 paper
NM_012092.4
p.G58R
c.172G>C
1 paper
NM_012092.4
p.G58E
c.173G>A
2 papers
NM_012092.4
p.G58G
c.174G>C
1 paper
NM_012092.4
p.G59W
c.175G>T
1 paper
NM_012092.4
p.Q60fs
c.178_179fs
1 paper
NM_012092.4
p.D64N
c.190G>A
1 paper
NM_012092.4
p.F51S
c.152T>C
2 papers
NM_012092.4
p.T68_K69insFs
c.204_205insA
1 paper
NM_012092.4
p.T68I
c.203C>T
1 paper
NM_012092.4
p.D46D
c.138C>T
1 paper
NM_012092.4
p.K69R
c.206A>G
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."