Varaico: Literature-Extracted Genetic Variants

Gene:IDH2
Variant:p.P151A

IDH2

2,456 papers

RefSeq Summary

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor...

Pfam Domains

Iso_dhaa 45–441UCSCIsocitrate/isopropylmalate dehydrogenase

Gene Aliases

HGNC Name

isocitrate dehydrogenase (NADP(+)) 2

HGNC Alias Symbol

IDH-2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_002168.4
p.P151A
c.451C>G
Surrounding Variants
1 paper
NM_002168.4
p.P151T
c.451C>A
1 paper
NM_002168.4
p.E150fs
c.448_449fs
1 paper
NM_002168.4
p.P151H
c.452C>A
1 paper
NM_002168.4
p.P151P
c.453C>T
1 paper
NM_002168.4
p.E150G
c.449A>G
1 paper
NM_002168.4
p.E150A
c.449A>C
1 paper
NM_002168.4
p.E150K
c.448G>A
1 paper
NM_002168.4
p.I152S
c.455T>G
1 paper
NM_002168.4
p.R149L
c.446G>T
3 papers
NM_002168.4
p.R149Q
c.446G>A
1 paper
NM_002168.4
p.R149Fs
c.445_446delinsGGTATCTFs
2 papers
NM_002168.4
p.R149W
c.445C>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."